Molecular and Cellular Biology® (MCB) showcases fundamental discoveries in gene expression and genome organization, cellular morphology and function, molecular metabolism, cellular trafficking, and signal transduction. The journal also is interested in studies that investigate molecular, cellular, and systemic host responses to pathogenic agents in chronic diseases and conditions.
MCB is edited by leading investigators in the field of molecular biology, and decisions are based solely on scientific merit. MCB recognizes that rigorous, in-depth extensions of prior observations contribute in an important way to the advancement of scientific knowledge. We welcome studies that build upon, clarify, or question previous work in the field and thereby move the field forward.
Current Issue :March 2018, Volume 38, Issue 6
Spotlights in the Current Issue:
After discovering a novel organelle found in protozoan parasites, the University of Pennsylvania’s Roos created a widely used eukaryotic pathogen database.
How to analyze ancient proteins
Previously considered immobile, these cells swoop in to seal epithelial holes and clean up cellular detritus.
Nobel PrizeâWinning Biologist Dies
By Catherine Offord | February 20, 2018
Günter Blobel, known for his work on the signal hypothesis of protein targeting, has died from cancer at age 81.
Stem cells and cancer cells have enough molecular similarities that the former can be used to trigger immunity against the latter.
Pectin fragments may signal plant cells to maintain a type of growth suited to darkness.
Image of the Day: Red-Hot Mitochondria
By The Scientist Staff | January 29, 2018
Mitochondria may sustain temperatures more than 10 °C warmer than human cells, say researchers.
The findings more than double the number of known defense mechanisms, piquing the interests of molecular biology tool developers.
Glial Ties to Persistent Pain
By Mark R. Hutchinson | January 1, 2018
Immune-like cells in the central nervous system are now recognized as key participants in the creation and maintenance of persistent pain.
Infographic: A Painful Pathway
By Catherine Offord | January 1, 2018
Since the mid-2000s, the voltage-gated sodium channel NaV1.7 has emerged as a promising target for a new class of analgesics.